- Irregular or no menstrual periods
- Patients have abnormal menstruation-menstrual period gap is 35 days to 6 months, approximately 3-6 menstrual periods per year) or secondary amenorrhea (an absence of menstrual for 6 months).
- Dysfunctional uterine bleeding and infertility are the other consequences of anovulatory menstrual cycles
- Chronic anovulation. (Absence of egg)
- Some women have Oligomenorrhoea (means very less menstrual bleeding…)
- The menstrual irregularities in PCOS usually manifest around the time of menarche.
- Obesity, weight gain, Obesity is present in nearly half of all women with PCOS.
- In women, metabolic syndrome is characterized by abdominal obesity (waist circumference > 35 in.),
- Excess hair growth-Hair is commonly seen on the upper lip, chin, around the nipples, and in lower abdomen.
- Some patients have acne and/or male-pattern hair loss (androgenic alopecia).
- Hyper androgenism clinically manifests as excess terminal body hair in a male distribution
pattern- A few patients may also have increased muscle mass, deepening voice, and/or clitoromegaly due to excessive androgens.
- Acne,
- Oily skin,
- Dandruff,
- Infertility,
- A subset of women with PCOS is infertile.
- Most women with PCOS ovulate intermittently. Pregnancy may take longer than in other women, or women with PCOS may have fewer children than they had planned
- Skin discolorations,
- High cholesterol levels,
- Elevated blood pressure,
- Abnormal hair growth.
- Sleep apnoea: Many women with PCOS have obstructive sleep apnoea syndrome. These patients have excessive daytime somnolence and have apnoea/ hypopnoea episodes
during sleep.
- Hirsutism: Patients may have excessive body hair in a male distribution pattern and acne. Some patients have virilizing signs, such as male-pattern balding or alopecia, increased muscle mass, deepening voice, or clitoromegaly; these findings should prompt a search for other causes of hyper androgenism.
- Obesity: Most of women with PCOS have abdominal obesity characterized by a waist circumference of greater than 35 in (>88 cm).
- Acanthosis nigricans: This is a diffuse, velvety thickening and hyper pigmentation of the skin. It may be present at the nape of the neck, axillae, area beneath the breasts, intertriginous areas, and exposed areas (e.g., elbows, knuckles). In patients with PCOS, acanthosis nigricans is thought to be the result of insulin resistance.
- Blood pressure: Patients may have elevated blood pressure with a systolic blood pressure of 130 mm Hg or higher and diastolic blood pressure of 85 mm of Hg or higher.
- Birth control pills
- Clomiphene citrate
- Flutamide
- Spironolactone
produce more FSH. This causes the egg to mature and be released. Sometimes women need stronger fertility drugs to get pregnant.
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